Metastasis‐associated 1 localizes to the sarcomeric Z‐disc and is implicated in skeletal muscle pathology

Metastasis‐associated 1 (MTA1), a subunit of the nucleosome remodeling and histone deacetylation (NuRD) corepressor complex, was reported to be expressed in the cytoplasm of skeletal muscles. However, the exact subcellular localization and the functional implications of MTA1 in skeletal muscles have...

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Veröffentlicht in:	Cytoskeleton (Hoboken, N.J.) N.J.), 2024-09, Vol.81 (9-10), p.427-435
Hauptverfasser:	Xue, Hongsheng, Han, Li, Sun, Haidi, Piao, Zhe, Cao, Wenjun, Qian, Haili, Zhao, Zhilong, Lang, Ming‐Fei, Gu, Chundong
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinin Cardiac muscle Cell survival Cytoplasm Deacetylation Dermatomyositis Duchenne's muscular dystrophy Gene expression Histones Immunoelectron microscopy Immunofluorescence Immunohistochemistry Localization Metastases Metastasis metastasis‐associated 1 Muscular dystrophy Musculoskeletal system Myopathy Nemaline myopathy pathogenesis Pathology sarcomere Sarcomeres Skeletal muscle Western blotting
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