Neurogenic-derived 6-nitrodopamine is the most potent endogenous modulator of the mouse urinary bladder relaxation

6-Nitrodopamine (6-ND) modulates vas deferens, seminal vesicles, and corpus cavernosum contractility; however, its role on the lower urinary tract organs has not been evaluated. Investigations of isolated urinary bladders from wild-type (WT) mice revealed 6-ND release was comparable to that of dopam...

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Veröffentlicht in:	Nitric oxide 2024-12, Vol.153, p.98-105
Hauptverfasser:	Oliveira, Mariana Gonçalves de, Britto-Junior, José, Martins Dias, Douglas Rafael, Pereira, Luise Gabriela Santos, Chiavegatto, Silvana, Hermawan, Idam, Shimokawa, Hiroaki, Tsutsui, Masato, Antunes, Edson, Nucci, Gilberto De
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Catecholamines Detrusor smooth muscle LC-MS/MS Male Mice Mice, Inbred C57BL Mice, Knockout Muscle Relaxation - drug effects Muscle, Smooth - drug effects Muscle, Smooth - physiology Nitric Oxide Synthase Type I - metabolism Nitric Oxide Synthase Type III - metabolism Sandwich bioassay Solid phase extraction Urinary Bladder - drug effects Urinary Bladder - metabolism Urinary Bladder - physiology
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