Solving the protein folding problem

The protein folding problem was, to paraphrase Churchill, ‘A riddle wrapped in a mystery inside an enigma’. The riddle, in this context, was the folding code; what interactions at the amino acid level are driving the folding process? The mystery was the kinetic question (Levinthal's paradox); h...

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Veröffentlicht in:	FEBS letters 2024-12, Vol.598 (23), p.2831-2835
1. Verfasser:	Sleator, Roy D.
Format:	Artikel
Sprache:	eng
Schlagworte:	AlphaFold ESMFold folding funnel hypothesis Folding@Home Foldit Humans Kinetics Models, Molecular Protein Folding Proteins - chemistry Proteins - genetics Proteins - metabolism RoseTTAFold zipping and assembly
Online-Zugang:	Volltext
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