5‑Hydroxytryptamine 1F Receptor Agonist Lasmiditan Differentially Regulates Successful Repair and Failed Repair Genes in a Mouse Model of Acute Kidney Injury

Increasing evidence substantiates the role of mitochondrial dysfunction, inflammation, fibrosis, and cell senescence in the onset and progression of acute kidney injury (AKI) to chronic kidney disease . The underlying governing cellular and transcriptional events, however, are not fully understood....

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Veröffentlicht in:ACS pharmacology & translational science 2024-10, Vol.7 (10), p.3045-3055
Hauptverfasser: Santiago Raj, Paul Victor, Scholpa, Natalie E., Hurtado, Kevin A., Janda, Jaroslav, Hortareas, John, Schnellmann, Rick G.
Format: Artikel
Sprache:eng
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