Preparation and characterization of an antibacterial CMC/PCL hydrogel films containing CIP/Cur: In vitro and in vivo evaluation of wound healing activity

Wound healing process significantly impeded by prolonged inflammation responses, infection at the wound site, and insufficient angiogenesis. The sustained release of anti-inflammation and anti-bacterial drugs has the potential to control immune responses, improve angiogenesis, accelerate wound heali...

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Veröffentlicht in:	International journal of biological macromolecules 2024-12, Vol.282 (Pt 1), p.136570, Article 136570
Hauptverfasser:	Mojahedi, Maryam, Heydari, Parisa, Kharazi, Anousheh Zargar
Format:	Artikel
Sprache:	eng
Schlagworte:	angiogenesis Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology antibacterial properties Carboxy methyl cellulose (CMC) carboxymethylcellulose cell movement Cell Movement - drug effects cell proliferation Cell Proliferation - drug effects ciprofloxacin Ciprofloxacin (CIP) Ciprofloxacin - administration & dosage Ciprofloxacin - chemistry Ciprofloxacin - pharmacology collagen curcumin Curcumin (Cur) Curcumin - chemistry Curcumin - pharmacology cytokines Drug Liberation Humans hydrogels Hydrogels - chemistry Hydrogels - pharmacology inflammation macrophages Male Mice Polycaprolactone (PCL) Polyesters - chemistry secretion water uptake Wound dressing Wound Healing - drug effects
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