New horizons in our understanding of precursor multiple myeloma and early interception

Multiple myeloma is an incurable plasma cell malignancy that evolves over decades through the selection and malignant transformation of monoclonal plasma cells. The evolution from precursor states to symptomatic disease is characterized by an increasing complexity of genomic alterations within the p...

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Veröffentlicht in:	Nature reviews. Cancer 2024-12, Vol.24 (12), p.867-886
Hauptverfasser:	Cordas dos Santos, David M., Toenges, Rosa, Bertamini, Luca, Alberge, Jean-Baptiste, Ghobrial, Irene M.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/251 631/67/1990/804 631/67/2195 631/67/580/1884 631/67/69 Animals Antibodies, Bispecific - therapeutic use Biomedical and Life Sciences Biomedicine Bispecific antibodies Cancer Research Chimeric antigen receptors Clinical trials Disease Progression Disease resistance Humans Immunotherapy, Adoptive - methods Lymphocytes Lymphocytes T Malignancy Microenvironments Multiple myeloma Multiple Myeloma - immunology Multiple Myeloma - therapy Plasma Plasma cells Plasma Cells - immunology Plasma Cells - pathology Review Article T-Lymphocytes - immunology Tumor Microenvironment Tumors
Online-Zugang:	Volltext
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