Development and Evaluation of Indole-Based Phospholipase D Inhibitors for Lung Cancer Immunotherapy

This study explored novel immunomodulatory approaches for cancer treatment, with a specific focus on lung cancer, the leading cause of cancer-related deaths worldwide. We synthesized indole-based phospholipase D (PLD) inhibitors with various substituents to improve anticancer efficacy. Through struc...

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Veröffentlicht in:	Journal of medicinal chemistry 2024-10
Hauptverfasser:	Song, Doona, Lim, Seong Hun, Kim, Yeji, Lee, Hyesung, Kim, Taehyun, Lim, Hocheol, Min, Do Sik, Han, Gyoonhee
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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