Microchannel percutaneous nephrolithotomy versus flexible ureteroscopic lithotripsy for the treatment of 1–2 cm high hardness single upper ureteral stones: a propensity score-matched study
The objective of this study was to compare the clinical efficacy and safety of microchannel percutaneous nephrolithotripsy (MPCNL) with flexible ureteroscopic lithotripsy (FURL) in the treatment of single upper ureteral stones with a diameter of 1–2 cm and high hardness. This study retrospectively a...
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| Veröffentlicht in: | Urolithiasis 2024-10, Vol.52 (1), p.143, Article 143 |
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| description | The objective of this study was to compare the clinical efficacy and safety of microchannel percutaneous nephrolithotripsy (MPCNL) with flexible ureteroscopic lithotripsy (FURL) in the treatment of single upper ureteral stones with a diameter of 1–2 cm and high hardness. This study retrospectively analyzed 89 patients diagnosed with a single upper ureteral stone with a 1–2 cm diameter and a computed tomography value > 1000 Hounsfield units. A propensity score matching system matched this study with factors to minimize the effect of baseline differences between patients. Ultimately, 29 patients in each of the two groups were successfully matched. The stone-free rate was marginally higher in the MPCNL group than in the FURL group (93.10% vs. 86.21%), although the difference did not reach statistical significance (
P
= 0.666). Furthermore, the mean operative time in the MPCNL group, although slightly longer than that in the FURL group, did not demonstrate a statistically significant difference (
P
= 0.833). However, patients in the MPCNL group exhibited a significantly more substantial decrease in hemoglobin than those in the FURL group (
P
|
| doi_str_mv | 10.1007/s00240-024-01641-9 |
| format | Article |
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P
= 0.666). Furthermore, the mean operative time in the MPCNL group, although slightly longer than that in the FURL group, did not demonstrate a statistically significant difference (
P
= 0.833). However, patients in the MPCNL group exhibited a significantly more substantial decrease in hemoglobin than those in the FURL group (
P
< 0.001) and a substantially more extended postoperative hospital stay (
P
< 0.001). Regarding perioperative complications, the incidence of moderate pain was higher in the MPCNL group than in the FURL group (
P
= 0.037). The difference in overall complication rates between the two groups did not reach statistical significance (
P
= 0.108). MPCNL and FURL are efficacious surgical procedures for treating single upper ureteral stones with a 1–2 cm diameter and high hardness.</description><identifier>ISSN: 2194-7236</identifier><identifier>ISSN: 2194-7228</identifier><identifier>EISSN: 2194-7236</identifier><identifier>DOI: 10.1007/s00240-024-01641-9</identifier><identifier>PMID: 39402382</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Aged ; Female ; Hardness ; Humans ; Kidney stones ; Length of Stay - statistics & numerical data ; Lithotripsy - adverse effects ; Lithotripsy - methods ; Male ; Medical Biochemistry ; Medicine ; Medicine & Public Health ; Middle Aged ; Nephrolithotomy, Percutaneous - adverse effects ; Nephrolithotomy, Percutaneous - methods ; Nephrology ; Operative Time ; Postoperative Complications - epidemiology ; Postoperative Complications - etiology ; Propensity Score ; Retrospective Studies ; Treatment Outcome ; Ureteral Calculi - surgery ; Ureteral Calculi - therapy ; Ureteroscopy - adverse effects ; Ureteroscopy - methods ; Urology</subject><ispartof>Urolithiasis, 2024-10, Vol.52 (1), p.143, Article 143</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024 Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><rights>Copyright Springer Nature B.V. Dec 2024</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c256t-3f8e3c4d661df6c7326ab977306db77c970c971e3f827308208a97c4d663ac4f3</cites><orcidid>0000-0002-7650-8842</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00240-024-01641-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00240-024-01641-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39402382$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Ganlin</creatorcontrib><creatorcontrib>Pan, Tingan</creatorcontrib><creatorcontrib>Zhou, Yijun</creatorcontrib><creatorcontrib>Dai, Xiaonong</creatorcontrib><creatorcontrib>Zhang, Zhenglin</creatorcontrib><creatorcontrib>Li, Wenjian</creatorcontrib><title>Microchannel percutaneous nephrolithotomy versus flexible ureteroscopic lithotripsy for the treatment of 1–2 cm high hardness single upper ureteral stones: a propensity score-matched study</title><title>Urolithiasis</title><addtitle>Urolithiasis</addtitle><addtitle>Urolithiasis</addtitle><description>The objective of this study was to compare the clinical efficacy and safety of microchannel percutaneous nephrolithotripsy (MPCNL) with flexible ureteroscopic lithotripsy (FURL) in the treatment of single upper ureteral stones with a diameter of 1–2 cm and high hardness. This study retrospectively analyzed 89 patients diagnosed with a single upper ureteral stone with a 1–2 cm diameter and a computed tomography value > 1000 Hounsfield units. A propensity score matching system matched this study with factors to minimize the effect of baseline differences between patients. Ultimately, 29 patients in each of the two groups were successfully matched. The stone-free rate was marginally higher in the MPCNL group than in the FURL group (93.10% vs. 86.21%), although the difference did not reach statistical significance (
P
= 0.666). Furthermore, the mean operative time in the MPCNL group, although slightly longer than that in the FURL group, did not demonstrate a statistically significant difference (
P
= 0.833). However, patients in the MPCNL group exhibited a significantly more substantial decrease in hemoglobin than those in the FURL group (
P
< 0.001) and a substantially more extended postoperative hospital stay (
P
< 0.001). Regarding perioperative complications, the incidence of moderate pain was higher in the MPCNL group than in the FURL group (
P
= 0.037). The difference in overall complication rates between the two groups did not reach statistical significance (
P
= 0.108). MPCNL and FURL are efficacious surgical procedures for treating single upper ureteral stones with a 1–2 cm diameter and high hardness.</description><subject>Adult</subject><subject>Aged</subject><subject>Female</subject><subject>Hardness</subject><subject>Humans</subject><subject>Kidney stones</subject><subject>Length of Stay - statistics & numerical data</subject><subject>Lithotripsy - adverse effects</subject><subject>Lithotripsy - methods</subject><subject>Male</subject><subject>Medical Biochemistry</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Nephrolithotomy, Percutaneous - adverse effects</subject><subject>Nephrolithotomy, Percutaneous - methods</subject><subject>Nephrology</subject><subject>Operative Time</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative Complications - etiology</subject><subject>Propensity Score</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><subject>Ureteral Calculi - surgery</subject><subject>Ureteral Calculi - therapy</subject><subject>Ureteroscopy - adverse effects</subject><subject>Ureteroscopy - methods</subject><subject>Urology</subject><issn>2194-7236</issn><issn>2194-7228</issn><issn>2194-7236</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU2O1TAMxysEYkbDXIAFisSGTSFfkzTs0IgvaRAbWFd5qfuaUZuUJEV0xx24ADdB4iicBM_r40MsiBQnsn_-27Kr6j6jjxml-kmmlEtao6kpU5LV5lZ1ypmRteZC3f7rf1Kd53xN8RhjJKN3qxNhJOWi4afVtzfepegGGwKMZIbklmIDxCWTAPOQ4ujLEEucVvIRUkZ3P8InvxuBLAkKpJhdnL0jG5f8nFfSx0TKAKQksGWCUEjsCfvx-Qv__tVNZPD7gQw2dQFyJtmH_Y3ajMWPmnYkuUSMPiWWzCnOELIvK8FSCerJFjdAh8jSrfeqO70dM5wf37Pq_Yvn7y5f1VdvX76-fHZVO36hSi36BoSTnVKs65XTgiu7M1oLqrqd1s5oipcBchydDaeNNfqQIKyTvTirHm262M6HBXJpJ58djOM2rFYwppRuJJWIPvwHvY5LCtjdgZIXyjQCKb5ROP6cE_TtnPxk09oy2t5suN023KJpDxtuDSY9OEovuwm63ym_9omA2ICMobCH9Kf2f2R_ApXyt6Q</recordid><startdate>20241014</startdate><enddate>20241014</enddate><creator>Wang, Ganlin</creator><creator>Pan, Tingan</creator><creator>Zhou, Yijun</creator><creator>Dai, Xiaonong</creator><creator>Zhang, Zhenglin</creator><creator>Li, Wenjian</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7650-8842</orcidid></search><sort><creationdate>20241014</creationdate><title>Microchannel percutaneous nephrolithotomy versus flexible ureteroscopic lithotripsy for the treatment of 1–2 cm high hardness single upper ureteral stones: a propensity score-matched study</title><author>Wang, Ganlin ; Pan, Tingan ; Zhou, Yijun ; Dai, Xiaonong ; Zhang, Zhenglin ; Li, Wenjian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c256t-3f8e3c4d661df6c7326ab977306db77c970c971e3f827308208a97c4d663ac4f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Female</topic><topic>Hardness</topic><topic>Humans</topic><topic>Kidney stones</topic><topic>Length of Stay - statistics & numerical data</topic><topic>Lithotripsy - adverse effects</topic><topic>Lithotripsy - methods</topic><topic>Male</topic><topic>Medical Biochemistry</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Nephrolithotomy, Percutaneous - adverse effects</topic><topic>Nephrolithotomy, Percutaneous - methods</topic><topic>Nephrology</topic><topic>Operative Time</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative Complications - etiology</topic><topic>Propensity Score</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><topic>Ureteral Calculi - surgery</topic><topic>Ureteral Calculi - therapy</topic><topic>Ureteroscopy - adverse effects</topic><topic>Ureteroscopy - methods</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Ganlin</creatorcontrib><creatorcontrib>Pan, Tingan</creatorcontrib><creatorcontrib>Zhou, Yijun</creatorcontrib><creatorcontrib>Dai, Xiaonong</creatorcontrib><creatorcontrib>Zhang, Zhenglin</creatorcontrib><creatorcontrib>Li, Wenjian</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Urolithiasis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Ganlin</au><au>Pan, Tingan</au><au>Zhou, Yijun</au><au>Dai, Xiaonong</au><au>Zhang, Zhenglin</au><au>Li, Wenjian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Microchannel percutaneous nephrolithotomy versus flexible ureteroscopic lithotripsy for the treatment of 1–2 cm high hardness single upper ureteral stones: a propensity score-matched study</atitle><jtitle>Urolithiasis</jtitle><stitle>Urolithiasis</stitle><addtitle>Urolithiasis</addtitle><date>2024-10-14</date><risdate>2024</risdate><volume>52</volume><issue>1</issue><spage>143</spage><pages>143-</pages><artnum>143</artnum><issn>2194-7236</issn><issn>2194-7228</issn><eissn>2194-7236</eissn><abstract>The objective of this study was to compare the clinical efficacy and safety of microchannel percutaneous nephrolithotripsy (MPCNL) with flexible ureteroscopic lithotripsy (FURL) in the treatment of single upper ureteral stones with a diameter of 1–2 cm and high hardness. This study retrospectively analyzed 89 patients diagnosed with a single upper ureteral stone with a 1–2 cm diameter and a computed tomography value > 1000 Hounsfield units. A propensity score matching system matched this study with factors to minimize the effect of baseline differences between patients. Ultimately, 29 patients in each of the two groups were successfully matched. The stone-free rate was marginally higher in the MPCNL group than in the FURL group (93.10% vs. 86.21%), although the difference did not reach statistical significance (
P
= 0.666). Furthermore, the mean operative time in the MPCNL group, although slightly longer than that in the FURL group, did not demonstrate a statistically significant difference (
P
= 0.833). However, patients in the MPCNL group exhibited a significantly more substantial decrease in hemoglobin than those in the FURL group (
P
< 0.001) and a substantially more extended postoperative hospital stay (
P
< 0.001). Regarding perioperative complications, the incidence of moderate pain was higher in the MPCNL group than in the FURL group (
P
= 0.037). The difference in overall complication rates between the two groups did not reach statistical significance (
P
= 0.108). MPCNL and FURL are efficacious surgical procedures for treating single upper ureteral stones with a 1–2 cm diameter and high hardness.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>39402382</pmid><doi>10.1007/s00240-024-01641-9</doi><orcidid>https://orcid.org/0000-0002-7650-8842</orcidid></addata></record> |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Aged Female Hardness Humans Kidney stones Length of Stay - statistics & numerical data Lithotripsy - adverse effects Lithotripsy - methods Male Medical Biochemistry Medicine Medicine & Public Health Middle Aged Nephrolithotomy, Percutaneous - adverse effects Nephrolithotomy, Percutaneous - methods Nephrology Operative Time Postoperative Complications - epidemiology Postoperative Complications - etiology Propensity Score Retrospective Studies Treatment Outcome Ureteral Calculi - surgery Ureteral Calculi - therapy Ureteroscopy - adverse effects Ureteroscopy - methods Urology |
| title | Microchannel percutaneous nephrolithotomy versus flexible ureteroscopic lithotripsy for the treatment of 1–2 cm high hardness single upper ureteral stones: a propensity score-matched study |
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