Reproductive safety of STING agonists MSA-2 and manganese-MSA-2

MSA-2, as an oral molecule for activating STING signaling pathway to cure the tumor entering clinical trials. The toxicity of MSA-2 has aroused wide concern, especially the reproductive toxicity can not be ignored. We synthesized the STING agonist (MSA-2) and its derivative manganese-MSA-2 (MSA-2-Mn...

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Veröffentlicht in:	Toxicology research (Cambridge) 2024-10, Vol.13 (5), p.tfae172
Hauptverfasser:	Cai, Ya, He, Tian, Yang, Tao, Li, Yating, Yi, Lirong, Li, Wenqing, Zhou, Peng
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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