Supramolecular PEG-DNA-Ferrocene Nanogels for Synergistically Amplified Chemodynamic Therapy via Cascade Reactions

Chemodynamic therapy (CDT) has been limited by the tumor microenvironment, such as the low concentration of hydrogen peroxide (H2O2). The combination of therapeutic strategies that increase H2O2 with CDT can synergistically enhance the therapeutic effect. Herein, a novel supramolecular PEG-DNA-ferro...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomacromolecules 2024-11, Vol.25 (11), p.7123-7133
Hauptverfasser:	Yan, Zhengwei, Duan, Zongze, Liu, Simin, Zhao, Zhiyong
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis Apoptosis - drug effects biocompatibility catalytic activity Cell Line, Tumor deoxyribonucleases DNA DNA - chemistry DNA - metabolism DNA damage ferrocenes Ferrous Compounds - chemistry Ferrous Compounds - pharmacology glucose oxidase Glucose Oxidase - chemistry Humans hydrogen peroxide Hydrogen Peroxide - chemistry Metallocenes - chemistry Metallocenes - pharmacology nanogels Nanogels - chemistry neoplasms oxygen consumption Polyethylene Glycols - chemistry Prodrugs - chemistry Prodrugs - pharmacology Reactive Oxygen Species - metabolism therapeutics Tirapazamine - chemistry Tirapazamine - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!