SMARCA4-deficient uterine tumors in young women: response to immune checkpoint inhibitors

SMARCA4-deficient tumors have been reported in various organs and are associated with a poor prognosis. SMARCA4-deficient undifferentiated uterine sarcoma (SDUS) was first described in 2018. Conversely, loss of SMARCA4 (BRG1) expression, as observed by immunostaining, has been observed in several ca...

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Veröffentlicht in:	International cancer conference journal 2024-10, Vol.13 (4), p.515-519
Hauptverfasser:	Suzui, Riku, Taki, Mana, Kitamura, Sachiko, Sunada, Masumi, Yamanoi, Koji, Murakami, Ryusuke, Yamaguchi, Ken, Hamanishi, Junzo, Minamiguchi, Sachiko, Mandai, Masaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Appendectomy Blood tests Bone cancer BRG1 protein Carcinoma Case report - Immunotherapy Case reports Chemotherapy Endometrium Hysterectomy Immune checkpoint inhibitors Kinases Lymphatic system Medical prognosis Medicine Medicine & Public Health Metastases Metastasis Morphology Mutation Oncology Oophorectomy Patients Pembrolizumab Sarcoma Surgery Surgical Oncology Tumors Uterine cancer Uterus Women
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