Autism spectrum disorder-like behaviors induced by hyper-glutamatergic NMDA receptor signaling through hypo-serotonergic 5-HT1A receptor signaling in the prefrontal cortex in mice exposed to prenatal valproic acid

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by repetitive behaviors, social deficits, and cognitive impairments. Maternal use of valproic acid (VPA) during pregnancy is associated with an increased risk of ASD in offspring. The prevailing pathophysiological hypothes...

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Veröffentlicht in:Neuropsychopharmacology (New York, N.Y.) N.Y.), 2024-10
Hauptverfasser: Kurahashi, Hitomi, Kunisawa, Kazuo, Tanaka, Kenji F., Kubota, Hisayoshi, Hasegawa, Masaya, Miyachi, Mai, Moriya, Yuka, Hasegawa, Yoichi, Nagai, Taku, Saito, Kuniaki, Nabeshima, Toshitaka, Mouri, Akihiro
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Sprache:eng
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