Effects of sildenafil on gas exchange, ventilatory, and sensory responses to exercise in subjects with mild-to-moderate COPD: A randomized cross-over trial

Excess exercise ventilation (high ventilation (V̇E)/carbon dioxide output (V̇CO2)) contributes significantly to dyspnea and exercise intolerance since the earlier stages of chronic obstructive pulmonary disease (COPD). A selective pulmonary vasodilator (inhaled nitric oxide) has shown to increase ex...

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Veröffentlicht in:	Respiratory physiology & neurobiology 2025-01, Vol.331, p.104359, Article 104359
Hauptverfasser:	Gass, Ricardo, Plachi, Franciele, Silva, Fernanda O.B., Nolasco, Talmir, Tonetto, Mateus Samuel, Goelzer, Leandro S., Muller, Paulo T., Knorst, Marli M., Neder, J. Alberto, Berton, Danilo C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic Obstructive Pulmonary Disease Dyspnea Exercise Test Phosphodiesterase Inhibitors 5
Online-Zugang:	Volltext
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