Jamming of nephron-forming niches in the developing mouse kidney creates cyclical mechanical stresses

Urinary collecting tubules form during kidney embryogenesis through the branching of the ureteric bud epithelium. A travelling mesenchyme niche of nephron progenitor cells caps each branching ureteric bud tip. These ‘tip domain’ niches pack more closely over developmental time and their number relat...

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Veröffentlicht in:	Nature materials 2024-10, Vol.23 (11), p.1582-1591
Hauptverfasser:	Prahl, Louis S., Liu, Jiageng, Viola, John M., Huang, Aria Zheyuan, Chan, Trevor J., Hayward-Lara, Gabriela, Porter, Catherine M., Shi, Chenjun, Zhang, Jitao, Hughes, Alex J.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136 639/166 Biomaterials Cells (biology) Chemistry and Materials Science Condensed Matter Physics Cytokeratin Decision making Embryonic growth stage Engineering Geometry Jamming Kidneys Materials Science Mechanics Nanotechnology Optical and Electronic Materials Rigidity Stiffening Stresses
Online-Zugang:	Volltext
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