Fetuin-B Interacts With Insulin Receptor-β and Promotes Insulin Resistance in Retina Cells

The purpose of this study was to investigate the correlation between insulin and Fetuin-B (FETUB) and the influence of FETUB on insulin signaling pathway in diabetic retinopathy (DR). Enzyme-linked immunosorbent assay (ELISA) was used to analyze FETUB and insulin levels in the serum and aqueous flui...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2024-10, Vol.65 (12), p.16
Hauptverfasser:	Zhang, Wenyi, Wang, Xin, Tian, Shuwei, Wang, Jianming, Zhou, Aiyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aqueous Humor - metabolism Blotting, Western Cells, Cultured Diabetic Retinopathy - genetics Diabetic Retinopathy - metabolism Enzyme-Linked Immunosorbent Assay Ependymoglial Cells - metabolism Female Fetuin-B - genetics Fetuin-B - metabolism Humans Immunoprecipitation Insulin - metabolism Insulin - pharmacology Insulin Resistance - physiology Male Mice Mice, Inbred C57BL Middle Aged Real-Time Polymerase Chain Reaction Receptor, Insulin - genetics Receptor, Insulin - metabolism Retinal Pigment Epithelium - metabolism Signal Transduction - physiology
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