Repeated radon exposure induced ATM kinase-mediated DNA damage response and protective autophagy in mice and human bronchial epithelial cells

Radon ( Rn) is a naturally occurring radioactive gas that has been closely linked with the development of lung cancer. In this study, we investigated the radon-induced DNA strand breaks, a critical event in lung carcinogenesis, and the corresponding DNA damage response (DDR) in mice and human bronch...

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Veröffentlicht in:	Toxicology research (Cambridge) 2024-10, Vol.13 (5), p.tfae165
Hauptverfasser:	Chen, Xiaoyu, Shan, Shan, Wang, Aiqing, Tu, Cheng, Wan, Jianmei, Hong, Chengjiao, Li, Xiaohan, Wang, Xueying, Yin, Jieyun, Tong, Jian, Tian, Hailin, Xin, Lili
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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