The multifaceted roles of phosphoethanolamine-modified lipopolysaccharides: from stress response and virulence to cationic antimicrobial resistance

SUMMARYLipopolysaccharides (LPS) are an integral part of the outer membrane of Gram-negative bacteria and play essential structural and functional roles in maintaining membrane integrity as well as in stress response and virulence. LPS comprises a membrane-anchored lipid A group, a sugar-based core...

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Veröffentlicht in:	Microbiology and molecular biology reviews 2024-12, Vol.88 (4), p.e0019323
Hauptverfasser:	Schumann, Anna, Gaballa, Ahmed, Wiedmann, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Antimicrobial resistance Bacterial Proteins - genetics Bacterial Proteins - metabolism Drug Resistance, Bacterial Ethanolaminephosphotransferase - genetics Ethanolaminephosphotransferase - metabolism Ethanolamines - metabolism Gram-Negative Bacteria - drug effects Gram-Negative Bacteria - genetics Gram-Negative Bacteria - pathogenicity Host-Pathogen Interactions Humans Lipid A - metabolism Lipopolysaccharides Lipopolysaccharides - metabolism Microbial Genetics Review Stress, Physiological Virulence
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