Phlebotomy-induced anemia reduces oxygen-induced retinopathy severity and dampens retinal developmental transcriptomic pathways in rats

Phlebotomy-induced-anemia (PIA), which induces tissue hypoxia and angiogenesis, occurs universally among infants at risk for severe retinopathy of prematurity (ROP). We hypothesized that PIA exacerbates pathologic retinal neovascularization in ROP. We induced PIA to a hematocrit of 18% among rats un...

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Veröffentlicht in:	Pediatric research 2024-10
Hauptverfasser:	Ingolfsland, Ellen C, Molomjamts, Mandkhai, Foster, Ann, Lee, Haeyeon, Roehrich, Heidi, Morikuni, Amelia, Qureishy, Husaam, Tran, Phu V, McLoon, Linda K, Georgieff, Michael K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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