Pediatric Myelodysplastic Syndrome

Myelodysplastic syndromes (MDSs) are rare in children and have unique clinical manifestations and implications. To review the clinical features, pathogenesis, and classification of pediatric MDS. Published literature and personal experience. Pediatric MDS vastly differs from adult MDS. Evaluation fo...

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Veröffentlicht in:Archives of pathology & laboratory medicine (1976) 2024-10
Hauptverfasser: Inam, Zaina, Pan, Miao, Diab, Yaser, Schore, Reuven, Vatsayan, Anant, Cheng, Jinjun
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container_title Archives of pathology & laboratory medicine (1976)
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creator Inam, Zaina
Pan, Miao
Diab, Yaser
Schore, Reuven
Vatsayan, Anant
Cheng, Jinjun
description Myelodysplastic syndromes (MDSs) are rare in children and have unique clinical manifestations and implications. To review the clinical features, pathogenesis, and classification of pediatric MDS. Published literature and personal experience. Pediatric MDS vastly differs from adult MDS. Evaluation for the presence of an underlying germline predisposition syndrome is critical for optimal classification and management. Because of the rarity of cases, resources to aid with the recognition, diagnosis, and management of pediatric MDS are limited, and multi-institutional collaborative studies are needed for the future.
doi_str_mv 10.5858/arpa.2024-0164-RA
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title Pediatric Myelodysplastic Syndrome
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