Eliminating Intracellular MRSA via Mannosylated Lipid-Coated Calcium Phosphate Nanoparticles

Methicillin-resistant Staphylococcus aureus (MRSA) within cells proves exceptionally challenging to eradicate using conventional antimicrobials, resulting in recurring infections and heightened resistance. Herein, we reported an innovative mannosylated lipid-coated photodynamic/photothermal calcium...

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Veröffentlicht in:	Molecular pharmaceutics 2024-11, Vol.21 (11), p.5772-5783
Hauptverfasser:	Chen, Xiangjun, Shi, Xiaoyi, Liu, Xiao, Zhai, Xuanxiang, Li, Wenting, Hong, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Calcium Phosphates - chemistry Female Humans Indocyanine Green - administration & dosage Indocyanine Green - chemistry Lipids - chemistry Macrophages - drug effects Mannose - chemistry Methicillin-Resistant Staphylococcus aureus - drug effects Mice Mice, Inbred BALB C Nanoparticles - chemistry Photochemotherapy - methods Photothermal Therapy - methods RAW 264.7 Cells Staphylococcal Infections - drug therapy
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