Psilocybin reduces functional correlation and the encoding of spatial information by neurons in mouse retrosplenial cortex

Psychedelic drugs have profound effects on perception, cognition and mood. How psychedelics affect neural signaling to produce these effects remains poorly understood. We investigated the effect of the classic psychedelic psilocybin on neural activity patterns and spatial encoding in the retrospleni...

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Veröffentlicht in:	The European journal of neuroscience 2024-11, Vol.60 (10), p.6395-6407
Hauptverfasser:	Ivan, Victorita E, Tomàs-Cuesta, David P, Esteves, Ingrid M, Luczak, Artur, Mohajerani, Majid, McNaughton, Bruce L, Gruber, Aaron J
Format:	Artikel
Sprache:	eng
Schlagworte:	Activity patterns Animals Cognition Gyrus Cinguli - drug effects Gyrus Cinguli - physiology Hallucinogens - pharmacology Ketanserin Ketanserin - pharmacology Male Mice Mice, Inbred C57BL Neural coding Neurons Neurons - drug effects Neurons - physiology Psilocybin Psilocybin - pharmacology Psychedelic drugs Serotonin 5-HT2 Receptor Antagonists - pharmacology Space Perception - drug effects Space Perception - physiology Spatial discrimination
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