Almond polysaccharides inhibit DSS-induced inflammatory response in ulcerative colitis mice through NF-κB pathway

Ulcerative colitis (UC), a type of inflammatory bowel disease (IBD), is a chronic recurrent inflammatory disease of the colon. Our previous findings demonstrated that almond polysaccharide (AP-1) exhibits significant anti-inflammatory activity in vitro. Therefore, this study aimed to explore the ame...

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Veröffentlicht in:	International journal of biological macromolecules 2024-11, Vol.281 (Pt 1), p.136206, Article 136206
Hauptverfasser:	Peng, Yanqi, Zhu, Jiayi, Li, Yingshuo, Yue, Xiqing, Peng, Yanyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Almond (Armeniaca Sibirica L. Lam.) Animals Anti-inflammatory Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology Colitis, Ulcerative - chemically induced Colitis, Ulcerative - drug therapy Colitis, Ulcerative - metabolism Colitis, Ulcerative - pathology Colon - drug effects Colon - metabolism Colon - pathology Cytokines - metabolism Dextran Sulfate - adverse effects Disease Models, Animal Inflammation - drug therapy Inflammation - pathology Male Mice NF-kappa B - metabolism NF-κB pathway Nitric Oxide Synthase Type II - metabolism Polysaccharide Polysaccharides - chemistry Polysaccharides - pharmacology Prunus dulcis - chemistry Signal Transduction - drug effects Ulcerative colitis
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