Ultrasensitive SERS Detection of Five β‑Blockers Achieved Using Chemometrics with a Two-Dimensional Substrate Formed by Large-Sized Ag@SiO2 Nanoparticles

We report on a surface-enhanced Raman scattering (SERS) platform for the detection of five beta-blockers (β-blockers): atenolol, esmolol, labetalol, sotalol, and propranolol. Key to this platform was a two-dimensional substrate formed by self-assembling large Ag@SiO2 nanoparticles (Ag@SiO2 NPs) on a...

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Veröffentlicht in:	Analytical chemistry (Washington) 2024-10, Vol.96 (41), p.16379-16386
Hauptverfasser:	Cheng, Tao, Xie, Ziyue, Wang, Tianrun, Jiang, Yuning, Guo, Xiaoyu, Liu, Xinling, Wen, Ying, Yang, Haifeng, Wu, Yiping
Format:	Artikel
Sprache:	eng
Schlagworte:	Atenolol Beta blockers Cluster analysis Detection limits Drug screening Drugs Electromagnetic fields Nanoparticles Principal components analysis Propranolol Raman spectra Raman spectroscopy Self-assembly Silicon dioxide Silicon wafers Silver Target detection
Online-Zugang:	Volltext
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