Alginate Oligosaccharides Enhance Gut Microbiota and Intestinal Barrier Function, Alleviating Host Damage Induced by Deoxynivalenol in Mice

Alginate oligosaccharides (AOS) exhibits notable effects in terms of anti-inflammatory, antibacterial, and antioxidant properties. Deoxynivalenol (DON) has the potential to trigger intestinal inflammation by upregulating pro-inflammatory cytokines and apoptosis, thereby compromising the integrity of...

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Veröffentlicht in:	The Journal of nutrition 2024-11, Vol.154 (11), p.3190-3202
Hauptverfasser:	Mi, Jinqiu, Tong, Yaoyi, Zhang, Qiyue, Wang, Qingfeng, Wang, Yanwei, Wang, Yue, Lin, Gang, Ma, Qiugang, Li, Tiantian, Huang, Shimeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Acclimatization Acetic acid alginate oligosaccharides Alginates Alginates - pharmacology Alginic acid Animals Apoptosis Body weight Colon Damage assessment Deoxynivalenol Dietary supplements Digestive system Epithelial cells Epithelium Exposure Gastrointestinal diseases Gastrointestinal Microbiome - drug effects Gastrointestinal tract gut microbiota Inflammation inflammatory Intestinal Barrier Function Intestinal microflora Intestinal Mucosa - drug effects Intestinal Mucosa - metabolism Intestine Intestines - drug effects Jejunum Laboratory animals Male Mice Microbiota Microorganisms Mucin Oligosaccharides Oligosaccharides - administration & dosage Oligosaccharides - pharmacology Probiotics Proteins Trichothecenes - toxicity Weight loss
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