Embracing multiple infection models to tackle Q fever: A review of in vitro, in vivo, and lung ex vivo models

•Coxiella burnetii (Q fever) cellular and animal infection models, pros and cons.•Mice and guinea pigs are cost effective unlike non-human primates.•Ex vivo lung platform allows examination of disease-relevant innate immune signaling.•All animal models are used for vaccine development, while innate...

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