Therapeutic potential of a novel hybrid protein: Mitigating allergy and airway remodeling in chronic asthma models induced by Dermatophagoides pteronyssinus

The house-dust mite Dermatophagoides pteronyssinus is a key trigger of allergic asthma. Therefore, it is essential to develop new vaccines that can alter inflammatory processes and airway remodeling. The goal of this study was to test the hypoallergenic and immunogenic characteristics of the hypoall...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular immunology 2024-11, Vol.175, p.121-131
Hauptverfasser:	Fernandes, Antônio Márcio Santana, da Silva, Eduardo Santos, Silva, Raphael Chagas, Silveira, Elisânia Fontes, Santiago, Leonardo Freire, de Andrade Belitardo, Emília Maria Medeiros, Alves, Vítor dos Santos, Bôas, Deise Souza Vilas, de Freitas, Luiz Antônio Rodrigues, Ferreira, Fatima, Jacquet, Alain, Pacheco, Luis Gustavo Carvalho, Alcantara-Neves, Neuza Maria, Pinheiro, Carina Silva
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway remodeling Airway Remodeling - drug effects Airway Remodeling - immunology Allergen-specific immunotherapy Allergens - immunology Animals Antigens, Dermatophagoides - immunology Asthma Asthma - immunology Asthma - pathology Chronic Disease Cytokines - immunology Cytokines - metabolism Dermatophagoides pteronyssinus Dermatophagoides pteronyssinus - immunology Disease Models, Animal Female Humans Hypersensitivity - immunology Hypoallergen Immunogenicity Immunoglobulin E - immunology Immunoglobulin G - immunology Male Mice Mice, Inbred BALB C Recombinant Fusion Proteins - immunology Recombinant Fusion Proteins - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!