Extended Sulfo-Pillar6arenes ─ a New Host Family and Its Application in the Binding of Direct Oral Anticoagulants

Herein, we report the synthesis of extended sulfo-pillar[6]arenes (sP6), a new host class with a pedigree in salt tolerance and ultrahigh binding affinity toward multiple drug classes. The parent sulfo-pillar[6]arene is a high-affinity host with the potential to act as a supramolecular reversal agen...

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Veröffentlicht in:	Journal of the American Chemical Society 2024-10
Hauptverfasser:	Wilson, Chelsea R, Puckett, Austia O, Murray, Isabella M, Oliver, Allen G, Hof, Fraser
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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