Brusatol improves the efficacy of sorafenib in Huh7 cells via ferroptosis resistance dependent Nrf2 signaling pathway

Hepatocellular carcinoma (HCC) is a common malignancy with a poor prognosis. The recommended treatment of unresectable HCC involves targeted therapy, for example sorafenib, combined with immunotherapy. A recent article reported that sorafenib could induce ferroptosis escape in HCC. Brusatol is a nov...

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Veröffentlicht in:	Biochemical and biophysical research communications 2024-11, Vol.734, p.150762, Article 150762
Hauptverfasser:	Liu, Xujin, Liu, Tianyi, Zhou, Zhonghua, Bian, Kai, Qiu, Cheng, Zhang, Fan
Format:	Artikel
Sprache:	eng
Schlagworte:	Brusatol Ferroptosis Hepatocellular carcinoma Nrf2 Sorafenib
Online-Zugang:	Volltext
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