Nanodrug delivery system constructed with dopamine-based functional molecules for efficient targeting of tumour cells

In order to enhance the water solubility of chemotherapeutic drugs, improve their biodistribution and narrow therapeutic window, two molecules of PDAO and FA-DAO with acid-sensitive Schiff base structure were designed and synthesized based on dopamine linolenate (DAO) in this paper, and subsequently...

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Veröffentlicht in:	RSC advances 2024-09, Vol.14 (42), p.3121-31216
Hauptverfasser:	Chen, Zhifeng, Dai, Jinglun, Fu, Nian, Yan, Zhihong, Zheng, Qinfang, Liu, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aqueous solutions Chemical synthesis Chemistry Dopamine Drug delivery systems Folic acid Imines Molecular structure Nanoparticles Solubility Tumors
Online-Zugang:	Volltext
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