CSF1-dependent macrophage support matrisome and epithelial stress-induced keratin remodeling in Eosinophilic esophagitis

[Display omitted] •Macrophage are increased in patients and a mouse model of fibrostenotic (FS-)EoE.•FS-EoE is defined by significant matrisome and wound healing responses.•Macrophage promote Tenascin C and Keratin 16 induction in EoE.•Macrophage depletion diminishes tissue remodeling in FS-EoE mice...

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Veröffentlicht in:	Mucosal immunology 2024-09
Hauptverfasser:	Benson, Taylor M., Markey, Gary E., Hammer, Juliet A., Simerly, Luke, Dzieciatkowska, Monika, Jordan, Kimberly R., Capocelli, Kelley E., Scullion, Kathleen M., Crowe, Louise, Ryan, Sinéad, Black, Jennifer O., Crue, Taylor, Andrews, Rachel, Burger, Cassandra, McNamee, Eóin N., Furuta, Glenn T., Menard-Katcher, Calies, Masterson, Joanne C.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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