Spatial transcriptomics reveal tumor microenvironment and SLCO2A1 correlated with tumor suppression in hypopharyngeal squamous cell carcinoma

•Spatial transcriptomic analysis was performed to unveil tumor microenvironment in HSCC for the first time.•Differentially expressed genes in epithelial, fibroblast, and immune cells of HSCC and lymphatic metastatic tissues were analyzed.•Correlation between SLCO2A1 and immune infiltration in HSCC w...

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Veröffentlicht in:	International immunopharmacology 2024-12, Vol.142 (Pt B), p.113243, Article 113243
Hauptverfasser:	Li, Ce, Xu, Chenyang, Guan, Rui, Jiao, Ruijie, Wang, Yin, Cui, Chengfu, Cao, Shengda, Chang, Fen, Wei, Ran, Li, Zinan, Liu, Zhiwei, Gross, Neil D, Li, Guojun, Li, Wenming, Wei, Dongmin, Lei, Dapeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Fibroblast cells HSCC Immune microenvironment SLCO2A1 Spatial transcriptomics
Online-Zugang:	Volltext
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