Review of machine learning for lipid nanoparticle formulation and process development

Lipid nanoparticles (LNPs) are a subset of pharmaceutical nanoparticulate formulations designed to encapsulate, stabilize, and deliver nucleic acid cargoes in vivo. Applications for LNPs include new interventions for genetic disorders, novel classes of vaccines, and alternate modes of intracellular...

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Veröffentlicht in:	Journal of pharmaceutical sciences 2024-09
Hauptverfasser:	Dorsey, Phillip J., Lau, Christina L., Chang, Ti-chiun, Doerschuk, Peter C., D'Addio, Suzanne M.
Format:	Artikel
Sprache:	eng
Schlagworte:	AI/ML Artificial intelligence Formulation and process development Lipid nanoparticle(s) LNP Machine learning Optimization
Online-Zugang:	Volltext
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