Uncommon Organisms in Neonatal Meningitis: Two Case Reports
These case reports describe two neonates, born at term, diagnosed with bacterial meningitis and septicemia caused by uncommon organisms. The clinical presentation, diagnostic reasoning, national guidelines, hospital course, and follow-up are discussed. Meningitis is among the differential diagnoses...
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| Veröffentlicht in: | Journal of pediatric health care 2025-01, Vol.39 (1), p.93-100 |
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| container_title | Journal of pediatric health care |
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| creator | Jean Ohns, Mary |
| description | These case reports describe two neonates, born at term, diagnosed with bacterial meningitis and septicemia caused by uncommon organisms. The clinical presentation, diagnostic reasoning, national guidelines, hospital course, and follow-up are discussed. Meningitis is among the differential diagnoses when there is a concern for neonatal sepsis. Concern for sepsis can arise from a variety of antepartum, intrapartum, and postpartum risk factors and present with a variety of symptoms. Neonatal sepsis is a significant cause of mortality, with 750,000 infant deaths annually. Effective treatment of neonatal sepsis requires timely diagnosis and tailored antimicrobial therapy that targets the causative pathogens. |
| doi_str_mv | 10.1016/j.pedhc.2024.08.011 |
| format | Article |
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The clinical presentation, diagnostic reasoning, national guidelines, hospital course, and follow-up are discussed. Meningitis is among the differential diagnoses when there is a concern for neonatal sepsis. Concern for sepsis can arise from a variety of antepartum, intrapartum, and postpartum risk factors and present with a variety of symptoms. Neonatal sepsis is a significant cause of mortality, with 750,000 infant deaths annually. Effective treatment of neonatal sepsis requires timely diagnosis and tailored antimicrobial therapy that targets the causative pathogens.</description><identifier>ISSN: 0891-5245</identifier><identifier>ISSN: 1532-656X</identifier><identifier>EISSN: 1532-656X</identifier><identifier>DOI: 10.1016/j.pedhc.2024.08.011</identifier><identifier>PMID: 39340517</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Anti-Bacterial Agents - therapeutic use ; Diagnosis, Differential ; Humans ; Infant, Newborn ; Male ; Meningitis ; Meningitis, Bacterial - diagnosis ; Meningitis, Bacterial - drug therapy ; Meningitis, Bacterial - microbiology ; Neonatal sepsis ; Neonatal Sepsis - diagnosis ; Neonatal Sepsis - drug therapy ; Neonatal Sepsis - microbiology ; Pediatric case report ; Salmonella ; Streptococcus group D</subject><ispartof>Journal of pediatric health care, 2025-01, Vol.39 (1), p.93-100</ispartof><rights>2024 National Association of Pediatric Nurse Practitioners</rights><rights>Copyright © 2024 National Association of Pediatric Nurse Practitioners. 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| ispartof | Journal of pediatric health care, 2025-01, Vol.39 (1), p.93-100 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Anti-Bacterial Agents - therapeutic use Diagnosis, Differential Humans Infant, Newborn Male Meningitis Meningitis, Bacterial - diagnosis Meningitis, Bacterial - drug therapy Meningitis, Bacterial - microbiology Neonatal sepsis Neonatal Sepsis - diagnosis Neonatal Sepsis - drug therapy Neonatal Sepsis - microbiology Pediatric case report Salmonella Streptococcus group D |
| title | Uncommon Organisms in Neonatal Meningitis: Two Case Reports |
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