The Role of Pyruvate Kinase M2 Posttranslational Modification in the Occurrence and Development of Hepatocellular Carcinoma

ABSTRACT Hepatocellular carcinoma (HCC) is one of the deadly malignant tumors that directly leads to the death of nearly one million people worldwide every year, causing a serious burden on society. In the presence of sufficient oxygen, HCC cells rapidly generate energy through aerobic glycolysis, w...

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Veröffentlicht in:	Cell biochemistry and function 2024-09, Vol.42 (7), p.e4125-n/a
Hauptverfasser:	Chunlian, Zhao, Qi, Wan, Rui, Zhao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Carrier Proteins - metabolism glycolysis hepatocellular carcinoma Humans Liver Neoplasms - metabolism Liver Neoplasms - pathology Membrane Proteins - metabolism posttranslational modification Protein Processing, Post-Translational Pyruvate Kinase - metabolism pyruvate kinase M2 Thyroid Hormone-Binding Proteins Thyroid Hormones - metabolism tumorigenesis and development
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