Expression of Programmed Death Ligand 1 and Indoleamine 2,3‐Dioxygenase in Oral Lichen Planus and Oral Lichenoid Lesions

ABSTRACT Background Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are inflammatory T‐cell mediated disorders of the oral mucosa (OM). Both are associated with an increased risk of oral squamous cell carcinoma, with OLL possibly having a higher rate of malignant transformation than OLP. P...

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Veröffentlicht in:	Journal of oral pathology & medicine 2024-11, Vol.53 (10), p.613-621
Hauptverfasser:	Kemppainen, Olli, Mathlin, Andreas, Pasonen‐Seppänen, Sanna, Siponen, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Apoptosis B7-H1 Antigen - biosynthesis Carcinogenesis Carcinoma, Squamous Cell - enzymology Carcinoma, Squamous Cell - pathology Cell death Dioxygenase Epithelium Female Humans IDO Immunohistochemistry Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism Lamina propria Lichen planus Lichen Planus, Oral - enzymology Lichen Planus, Oral - metabolism Lichen Planus, Oral - pathology Lichenoid Eruptions - enzymology Lichenoid Eruptions - pathology Ligands Male Middle Aged Mouth Mucosa - enzymology Mouth Mucosa - metabolism Mouth Mucosa - pathology Mouth Neoplasms - enzymology Mouth Neoplasms - pathology Oral cancer Oral carcinoma oral lichen planus oral lichenoid lesions oral potentially malignant disorder Oral squamous cell carcinoma PD-L1 protein PD‐L1 Squamous cell carcinoma
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