A review of the synthetic strategies toward the antiviral drug tecovirimat

This review provides a comprehensive analysis of synthetic routes for tecovirimat, an antiviral drug used to treat orthopoxvirus infections, including monkeypox and smallpox. We focus on the scale-up synthesis of key intermediates, including cycloheptatriene, as documented in the published literatur...

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Veröffentlicht in:Organic & biomolecular chemistry 2025-01, Vol.23 (2), p.239-254
Hauptverfasser: Bonku, Emmanuel Mintah, Qin, Hongjian, Odilov, Abdullajon, Abduahadi, Safomuddin, Guma, Samuel Desta, Zhu, Fuqiang, Shen, Jingshan
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Sprache:eng
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