Ultra-low dose estradiol and dydrogesterone for the treatment of menopausal symptoms in a pooled, multi-ethnic population

•Estradiol 0.5 mg/dydrogesterone 2.5 mg reduced menopausal vasomotor symptoms.•This ultra-low dose was associated with fewer hot flushes per day (vs placebo).•Women receiving the ultra-low-dose estradiol/dydrogesterone reported improved health-related quality of life.•Combined estradiol 0.5 mg/dydro...

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