Negatively Charged Thermosensitive Hydrogel Loaded with Pectin Microspheres to Recover the Mucosal Barrier for Ulcerative Colitis Therapy

Ulcerative colitis (UC), a chronic inflammatory bowel disease, poses a heightened colorectal cancer risk due to persistent mucosal inflammation and barrier dysfunction. In this article, a negatively charged thermosensitive hydrogel loaded with pectin microspheres was used as the enema for UC treatme...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomacromolecules 2024-10, Vol.25 (10), p.6801-6813
Hauptverfasser:	Chen, Shuqi, Gao, Wenxia, Ge, Pengjin, Chang, Shuhua, Wang, Ting, Zhao, Quan, He, Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anti-inflammatory agents Colitis, Ulcerative - drug therapy Colitis, Ulcerative - pathology colon colorectal neoplasms composite polymers Curcumin - administration & dosage Curcumin - chemistry Curcumin - pharmacology Drug Carriers - chemistry electrostatic interactions hydrogels Hydrogels - chemistry inflammation Intestinal Mucosa - drug effects Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Male Mesalamine - administration & dosage Mesalamine - chemistry Mesalamine - pharmacology Mice microparticles Microspheres pectins Pectins - chemistry risk succinic acid therapeutics thermosensitivity ulcerative colitis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!