Salidroside treatment decreases the susceptibility of atrial fibrillation in diabetic mice by reducing mTOR-STAT3-MCP-1 signaling and atrial inflammation

[Display omitted] •Diabetic atria exhibited enhanced chemokine/cytokine-mediated signaling and inflammatory response.•Salidroside dose-dependently reduced atrial remodeling and AF susceptibility in diabetic mice.•Overactivation of mTOR-STAT3 signaling mediated the production of MCP1 and diabetes-rel...

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Veröffentlicht in:	International immunopharmacology 2024-12, Vol.142 (Pt B), p.113196, Article 113196
Hauptverfasser:	Ren, Wenpu, Huang, Yuting, Meng, Shan, Cao, Zijun, Qin, Nana, Zhao, Jikai, Huang, Tao, Guo, Xiaodong, Chen, Xin, Zhou, Zijun, Zhu, Yan, Yu, Liming, Wang, Huishan
Format:	Artikel
Sprache:	eng
Schlagworte:	Atrial fibrillation MCP-1 mTOR Salidroside Type 2 diabetes mellitus
Online-Zugang:	Volltext
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