Ileocolic resection with temporary ileostomy for Crohn's disease: does it affect long-term disease recurrence compared with primary anastomosis?

Ileocolic resection with temporary ileostomy for Crohn's disease: does it affect long-term disease recurrence compared with primary anastomosis?

We aimed to assess whether the risk of disease recurrence in Crohn's disease (CD) patients that undergone ileocolic resection (ICR) with temporary ileostomy and a later stoma reversal is different compared to patients that underwent a one-stage operation. A single-center retrospective review of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:ANZ journal of surgery 2024-09
Hauptverfasser: Goldenshluger, Michael, Segev, Lior
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title ANZ journal of surgery
container_volume
creator Goldenshluger, Michael
Segev, Lior
description We aimed to assess whether the risk of disease recurrence in Crohn's disease (CD) patients that undergone ileocolic resection (ICR) with temporary ileostomy and a later stoma reversal is different compared to patients that underwent a one-stage operation. A single-center retrospective review of all patients that underwent elective primary ICR for CD between 2010 and 2022 divided into: 2S-ICR group-patients who underwent two-stage ICR. 1S-ICR group-patients who underwent one-stage ICR. The cohort included 191 patients (mean age 33.4, range 15-70), with 40 and 151 patients in the 2S-ICR and 1S-ICR groups, respectively. The 2S-ICR were more comorbid, with a lower mean BMI (18 vs. 21.3, P 
doi_str_mv 10.1111/ans.19237
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3108386831</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3108386831</sourcerecordid><originalsourceid>FETCH-LOGICAL-c175t-49dd40113486a4ebe3a7a934b7aa334a91bcdb6e63905578657bffc4febf70ca3</originalsourceid><addsrcrecordid>eNo9kU1OwzAQhS0EolBYcAHkHbBIiWsnjtkgVPFTqRIbWEeOM6ZGSRw8iVBvwZFJacpsZhbfvDeaR8gFi2dsqFvd4IypOZcH5IQJkURzpuThODPB-YScIn7GMUtTlRyTCVdzJSWXJ-RnWYE3vnKGBkAwnfMN_XbdmnZQtz7osKFuQLDz9YZaH-gi-HVzhbR0CBrhjpYekLqOamuHfVr55iPqINR7YhA2fQjQGKDG160OUO4s2uDqrYFu9Fbfo8P7M3JkdYVwPvYpeX96fFu8RKvX5-XiYRUZJpMuEqosRcwYF1mqBRTAtdSKi0JqzbnQihWmLFJIuYqTRGZpIgtrjbBQWBkbzafkeqfbBv_VA3Z57dBAVekGfI85Z3HGszTjbEBvdqgJHjGAzcfDcxbn2wDyIYD8L4CBvRxl-6KG8p_cf5z_Ah0khOk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3108386831</pqid></control><display><type>article</type><title>Ileocolic resection with temporary ileostomy for Crohn's disease: does it affect long-term disease recurrence compared with primary anastomosis?</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Goldenshluger, Michael ; Segev, Lior</creator><creatorcontrib>Goldenshluger, Michael ; Segev, Lior</creatorcontrib><description>We aimed to assess whether the risk of disease recurrence in Crohn's disease (CD) patients that undergone ileocolic resection (ICR) with temporary ileostomy and a later stoma reversal is different compared to patients that underwent a one-stage operation. A single-center retrospective review of all patients that underwent elective primary ICR for CD between 2010 and 2022 divided into: 2S-ICR group-patients who underwent two-stage ICR. 1S-ICR group-patients who underwent one-stage ICR. The cohort included 191 patients (mean age 33.4, range 15-70), with 40 and 151 patients in the 2S-ICR and 1S-ICR groups, respectively. The 2S-ICR were more comorbid, with a lower mean BMI (18 vs. 21.3, P &lt; 0.001), higher median ASA score (3 vs. 2, P = 0.036), higher percentage on pre-operative total parenteral nutrition (TPN) (62.5% vs. 24.5%, P &lt; 0.001), and lower levels of pre-operative albumin (3.3 g/dL vs. 3.8 g/dL, P &lt; 0.001). There were no significant differences in the overall postoperative complication rate (47.5% vs. 47.7% respectively, P = 1), nor in the rate of severe complications (17.5% vs. 13.2%, P = 0.6), but, the 2S-ICR had a longer post-operative length-of-stay (14 vs. 6 days, P &lt; 0.001) and higher rates of 30-day readmission (30% vs. 13.2%, P = 0.017). After an overall median follow-up of 63 months, the groups showed similar rates of endoscopic, clinical, and surgical recurrence. Two-stage ICR with a temporary ileostomy does not change long-term CD recurrence rates compared with one-stage ICR.</description><identifier>ISSN: 1445-1433</identifier><identifier>ISSN: 1445-2197</identifier><identifier>EISSN: 1445-2197</identifier><identifier>DOI: 10.1111/ans.19237</identifier><identifier>PMID: 39297737</identifier><language>eng</language><publisher>Australia</publisher><ispartof>ANZ journal of surgery, 2024-09</ispartof><rights>2024 Royal Australasian College of Surgeons.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c175t-49dd40113486a4ebe3a7a934b7aa334a91bcdb6e63905578657bffc4febf70ca3</cites><orcidid>0000-0001-7972-9424 ; 0000-0003-3701-2307</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39297737$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Goldenshluger, Michael</creatorcontrib><creatorcontrib>Segev, Lior</creatorcontrib><title>Ileocolic resection with temporary ileostomy for Crohn's disease: does it affect long-term disease recurrence compared with primary anastomosis?</title><title>ANZ journal of surgery</title><addtitle>ANZ J Surg</addtitle><description>We aimed to assess whether the risk of disease recurrence in Crohn's disease (CD) patients that undergone ileocolic resection (ICR) with temporary ileostomy and a later stoma reversal is different compared to patients that underwent a one-stage operation. A single-center retrospective review of all patients that underwent elective primary ICR for CD between 2010 and 2022 divided into: 2S-ICR group-patients who underwent two-stage ICR. 1S-ICR group-patients who underwent one-stage ICR. The cohort included 191 patients (mean age 33.4, range 15-70), with 40 and 151 patients in the 2S-ICR and 1S-ICR groups, respectively. The 2S-ICR were more comorbid, with a lower mean BMI (18 vs. 21.3, P &lt; 0.001), higher median ASA score (3 vs. 2, P = 0.036), higher percentage on pre-operative total parenteral nutrition (TPN) (62.5% vs. 24.5%, P &lt; 0.001), and lower levels of pre-operative albumin (3.3 g/dL vs. 3.8 g/dL, P &lt; 0.001). There were no significant differences in the overall postoperative complication rate (47.5% vs. 47.7% respectively, P = 1), nor in the rate of severe complications (17.5% vs. 13.2%, P = 0.6), but, the 2S-ICR had a longer post-operative length-of-stay (14 vs. 6 days, P &lt; 0.001) and higher rates of 30-day readmission (30% vs. 13.2%, P = 0.017). After an overall median follow-up of 63 months, the groups showed similar rates of endoscopic, clinical, and surgical recurrence. Two-stage ICR with a temporary ileostomy does not change long-term CD recurrence rates compared with one-stage ICR.</description><issn>1445-1433</issn><issn>1445-2197</issn><issn>1445-2197</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNo9kU1OwzAQhS0EolBYcAHkHbBIiWsnjtkgVPFTqRIbWEeOM6ZGSRw8iVBvwZFJacpsZhbfvDeaR8gFi2dsqFvd4IypOZcH5IQJkURzpuThODPB-YScIn7GMUtTlRyTCVdzJSWXJ-RnWYE3vnKGBkAwnfMN_XbdmnZQtz7osKFuQLDz9YZaH-gi-HVzhbR0CBrhjpYekLqOamuHfVr55iPqINR7YhA2fQjQGKDG160OUO4s2uDqrYFu9Fbfo8P7M3JkdYVwPvYpeX96fFu8RKvX5-XiYRUZJpMuEqosRcwYF1mqBRTAtdSKi0JqzbnQihWmLFJIuYqTRGZpIgtrjbBQWBkbzafkeqfbBv_VA3Z57dBAVekGfI85Z3HGszTjbEBvdqgJHjGAzcfDcxbn2wDyIYD8L4CBvRxl-6KG8p_cf5z_Ah0khOk</recordid><startdate>20240919</startdate><enddate>20240919</enddate><creator>Goldenshluger, Michael</creator><creator>Segev, Lior</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7972-9424</orcidid><orcidid>https://orcid.org/0000-0003-3701-2307</orcidid></search><sort><creationdate>20240919</creationdate><title>Ileocolic resection with temporary ileostomy for Crohn's disease: does it affect long-term disease recurrence compared with primary anastomosis?</title><author>Goldenshluger, Michael ; Segev, Lior</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c175t-49dd40113486a4ebe3a7a934b7aa334a91bcdb6e63905578657bffc4febf70ca3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Goldenshluger, Michael</creatorcontrib><creatorcontrib>Segev, Lior</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>ANZ journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goldenshluger, Michael</au><au>Segev, Lior</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ileocolic resection with temporary ileostomy for Crohn's disease: does it affect long-term disease recurrence compared with primary anastomosis?</atitle><jtitle>ANZ journal of surgery</jtitle><addtitle>ANZ J Surg</addtitle><date>2024-09-19</date><risdate>2024</risdate><issn>1445-1433</issn><issn>1445-2197</issn><eissn>1445-2197</eissn><abstract>We aimed to assess whether the risk of disease recurrence in Crohn's disease (CD) patients that undergone ileocolic resection (ICR) with temporary ileostomy and a later stoma reversal is different compared to patients that underwent a one-stage operation. A single-center retrospective review of all patients that underwent elective primary ICR for CD between 2010 and 2022 divided into: 2S-ICR group-patients who underwent two-stage ICR. 1S-ICR group-patients who underwent one-stage ICR. The cohort included 191 patients (mean age 33.4, range 15-70), with 40 and 151 patients in the 2S-ICR and 1S-ICR groups, respectively. The 2S-ICR were more comorbid, with a lower mean BMI (18 vs. 21.3, P &lt; 0.001), higher median ASA score (3 vs. 2, P = 0.036), higher percentage on pre-operative total parenteral nutrition (TPN) (62.5% vs. 24.5%, P &lt; 0.001), and lower levels of pre-operative albumin (3.3 g/dL vs. 3.8 g/dL, P &lt; 0.001). There were no significant differences in the overall postoperative complication rate (47.5% vs. 47.7% respectively, P = 1), nor in the rate of severe complications (17.5% vs. 13.2%, P = 0.6), but, the 2S-ICR had a longer post-operative length-of-stay (14 vs. 6 days, P &lt; 0.001) and higher rates of 30-day readmission (30% vs. 13.2%, P = 0.017). After an overall median follow-up of 63 months, the groups showed similar rates of endoscopic, clinical, and surgical recurrence. Two-stage ICR with a temporary ileostomy does not change long-term CD recurrence rates compared with one-stage ICR.</abstract><cop>Australia</cop><pmid>39297737</pmid><doi>10.1111/ans.19237</doi><orcidid>https://orcid.org/0000-0001-7972-9424</orcidid><orcidid>https://orcid.org/0000-0003-3701-2307</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 1445-1433
ispartof ANZ journal of surgery, 2024-09
issn 1445-1433
1445-2197
1445-2197
language eng
recordid cdi_proquest_miscellaneous_3108386831
source Wiley Online Library Journals Frontfile Complete
title Ileocolic resection with temporary ileostomy for Crohn's disease: does it affect long-term disease recurrence compared with primary anastomosis?
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T01%3A23%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Ileocolic%20resection%20with%20temporary%20ileostomy%20for%20Crohn's%20disease:%20does%20it%20affect%20long-term%20disease%20recurrence%20compared%20with%20primary%20anastomosis?&rft.jtitle=ANZ%20journal%20of%20surgery&rft.au=Goldenshluger,%20Michael&rft.date=2024-09-19&rft.issn=1445-1433&rft.eissn=1445-2197&rft_id=info:doi/10.1111/ans.19237&rft_dat=%3Cproquest_cross%3E3108386831%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3108386831&rft_id=info:pmid/39297737&rfr_iscdi=true