Electrooxidative C(sp 3 )-H Cyanation of Sparteine and Lupanine in Undivided Batch and Continuous-Flow Cells

Sparteine is widely used as a chiral ligand in asymmetric synthesis, but methods for providing efficient access to functionalized sparteine derivatives are still limited. Herein, we describe an electrochemical α-cyanation of sparteine-type bis-quinolizidine alkaloids. This method features commercial...

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Veröffentlicht in:ChemSusChem 2024-11, p.e202401305
Hauptverfasser: Durão, Raquel M, Clemente, Duarte B, Muiz, Abdullahi A, Lima, Sara, Carvalho, Daniel F, De Vos, Stijn, de Jesus, Rita, Fortuna, Andreia, Afonso, Carlos A M, Coelho, Jaime A S
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Sprache:eng
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