Laminar organization of visual responses in core and parabelt auditory cortex

Abstract Audiovisual (AV) interaction has been shown in many studies of auditory cortex. However, the underlying processes and circuits are unclear because few studies have used methods that delineate the timing and laminar distribution of net excitatory and inhibitory processes within areas, much l...

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Veröffentlicht in:Cerebral cortex (New York, N.Y. 1991) N.Y. 1991), 2024-09, Vol.34 (9)
Hauptverfasser: Mackey, Chase A, O’Connell, Monica N, Hackett, Troy A, Schroeder, Charles E, Kajikawa, Yoshinao
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container_issue 9
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container_title Cerebral cortex (New York, N.Y. 1991)
container_volume 34
creator Mackey, Chase A
O’Connell, Monica N
Hackett, Troy A
Schroeder, Charles E
Kajikawa, Yoshinao
description Abstract Audiovisual (AV) interaction has been shown in many studies of auditory cortex. However, the underlying processes and circuits are unclear because few studies have used methods that delineate the timing and laminar distribution of net excitatory and inhibitory processes within areas, much less across cortical levels. This study examined laminar profiles of neuronal activity in auditory core (AC) and parabelt (PB) cortices recorded from macaques during active discrimination of conspecific faces and vocalizations. We found modulation of multi-unit activity (MUA) in response to isolated visual stimulation, characterized by a brief deep MUA spike, putatively in white matter, followed by mid-layer MUA suppression in core auditory cortex; the later suppressive event had clear current source density concomitants, while the earlier MUA spike did not. We observed a similar facilitation-suppression sequence in the PB, with later onset latency. In combined AV stimulation, there was moderate reduction of responses to sound during the visual-evoked MUA suppression interval in both AC and PB. These data suggest a common sequence of afferent spikes, followed by synaptic inhibition; however, differences in timing and laminar location may reflect distinct visual projections to AC and PB.
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source Oxford University Press Journals All Titles (1996-Current); MEDLINE
subjects Acoustic Stimulation - methods
Action Potentials - physiology
Animals
Auditory Cortex - physiology
Auditory Perception - physiology
Female
Macaca mulatta
Male
Neurons - physiology
Photic Stimulation - methods
Visual Perception - physiology
Vocalization, Animal - physiology
title Laminar organization of visual responses in core and parabelt auditory cortex
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