Correlation between PD-1/PD-L1 and RANKL/OPG in chronic apical periodontitis model of Sprague-Dawley rats

[Abstract] Chronic apical periodontitis (CAP) is characterized by inflammation and destruction of the apical periodontium that is of pulpal origin, appearing as an apical radiolucent area, and does not produce clinical symptoms. Little is known about whether the PD-1/PD-L1 ratio is associated with t...

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Veröffentlicht in:	Odontology 2024-10, Vol.112 (4), p.1113-1122
Hauptverfasser:	Wang, Qi, Wang, Liping, Sheng, Li, Zhang, Bei, Jieensi, Burlen, Zheng, Shutao, Liu, Yishan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveolar bone Animals B7-H1 Antigen - metabolism Bone density Bone resorption Dentistry Disease Models, Animal Gene expression Gum disease Immunohistochemistry Male Mandible Medicine mRNA Oral and Maxillofacial Surgery Oral cavity Original Article Osteoprotegerin Osteoprotegerin - metabolism PD-1 protein PD-L1 protein Periapical Periodontitis - metabolism Periapical Periodontitis - pathology Periodontitis Periodontium Programmed Cell Death 1 Receptor - metabolism RANK Ligand - metabolism Rats Rats, Sprague-Dawley Real-Time Polymerase Chain Reaction Root resorption TRANCE protein
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