Identification of nontuberculous mycobacteria using the GenoType CMdirect and GenoType Mycobacterium CM line probe assays in GeneXpert MTB/RIF Ultra negative sputum: A South African prevalence study

•Prevalence of nontuberculous mycobacteria (NTM) among a GXP-negative cohort was 1.7 %.•CMdirect line probe assay showed a specificity of 100 % as a possible rule-in test.•Culture-independent molecular techniques on decontaminated sputum could aid in NTM identification. The GenoType CMdirect Ver 1.0...

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Veröffentlicht in:	Diagnostic microbiology and infectious disease 2024-12, Vol.110 (4), p.116531, Article 116531
Hauptverfasser:	Opperman, Christoffel, Johannes, Chaldene, Singh, Sarishna, Ghebrekristos, Yonas, Warren, Rob, Esmail, Aliasgar, Goosen, Wynand
Format:	Artikel
Sprache:	eng
Schlagworte:	Genotype GenoType CMdirect GenoType Mycobacterium CM Humans Molecular assay Molecular Diagnostic Techniques - methods Mycobacterium Infections, Nontuberculous - diagnosis Mycobacterium Infections, Nontuberculous - epidemiology Mycobacterium Infections, Nontuberculous - microbiology Nontuberculous mycobacteria Nontuberculous Mycobacteria - classification Nontuberculous Mycobacteria - genetics Nontuberculous Mycobacteria - isolation & purification Prevalence Sensitivity and Specificity South Africa South Africa - epidemiology Sputum Sputum - microbiology
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