SAR Analysis of Novel Coxsackie virus A9 Capsid Binders

Enterovirus infections are common in humans, yet there are no approved antiviral treatments. In this study we concentrated on inhibition of one of the Enterovirus B (EV-B), namely Coxsackievirus A9 (CVA9), using a combination of medicinal chemistry, virus inhibition assays, structure determination f...

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Veröffentlicht in:Journal of medicinal chemistry 2024-10, Vol.67 (19), p.17144-17161
Hauptverfasser: Tammaro, Chiara, Plavec, Zlatka, Myllymäki, Laura, Mitchell, Cristopher, Consalvi, Sara, Biava, Mariangela, Ciogli, Alessia, Domanska, Aušra, Leppilampi, Valtteri, Buckner, Cienna, Manetto, Simone, Sciò, Pietro, Coluccia, Antonio, Laajala, Mira, Dondio, Giulio M., Bigogno, Chiara, Marjomäki, Varpu, Butcher, Sarah J., Poce, Giovanna
Format: Artikel
Sprache:eng
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