Detection of Short-Chain Chlorinated Aliphatic Hydrocarbons through an Engineered Biosensor with Tailored Ligand Specificity

Short-chain chlorinated aliphatic hydrocarbons (SCAHs), commonly used as industrial reagents and solvents, pose a significant threat to ecosystems and human health as they infiltrate aquatic environments due to extensive usage and accidental spills. Whole-cell biosensors have emerged as cost-effecti...

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Veröffentlicht in:	Analytical chemistry (Washington) 2024-10, Vol.96 (39), p.15614-15623
Hauptverfasser:	Chen, Dongdong, Zhao, Jiadi, Xu, Shengmin, Wu, Lijun
Format:	Artikel
Sprache:	eng
Schlagworte:	Accidental spills Aliphatic hydrocarbons analytical chemistry Aquatic ecosystems Aquatic environment Biosensing Techniques - methods Biosensors Chlorinated hydrocarbons Cost analysis cost effectiveness detection limit Directed evolution Dynamic response Environmental monitoring evolution Flow Cytometry Fluorescence Gas chromatography gas chromatography-mass spectrometry human health Hydrocarbons Hydrocarbons, Chlorinated - analysis Leakage Ligands Mass spectrometry Mass spectroscopy Mutation promoter regions Promoter Regions, Genetic Reagents Real time remediation transcription (genetics) Transcription factors Transcription Factors - genetics Transcription Factors - metabolism Water analysis Water Pollutants, Chemical - analysis Water sampling
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