An experimental census of retrons for DNA production and genome editing

Retrons are bacterial immune systems that use reverse-transcribed DNA (RT-DNA) to detect phage infection. They are also deployed for genome editing, where they are modified so that the RT-DNA encodes an editing donor. Retrons are common in bacterial genomes, and thousands of unique retrons have been...

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Veröffentlicht in:	Nature biotechnology 2024-09
Hauptverfasser:	Khan, Asim G, Rojas-Montero, Matías, González-Delgado, Alejandro, Lopez, Santiago C, Fang, Rebecca F, Crawford, Kate D, Shipman, Seth L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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