Deacetylation by SIRT6 increases the stability of GILZ to suppress NSCLC cell migration and invasion

Glucocorticoid-induced leucine zipper (GILZ) plays a role in cancer cell proliferation in several tumor types. However, in our present study, GILZ was demonstrated to be a metastasis regulator but not a proliferation regulator in non-small cell lung cancer (NSCLC). The overexpression of GILZ had no...

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Veröffentlicht in:Cellular signalling 2024-12, Vol.124, p.111414, Article 111414
Hauptverfasser: Chen, Shiyin, Yang, Huaping, Hu, Zhenghui, Jin, Jiangbo, Xiong, Xiangyang, Zhang, Ziyu, Xie, Caifeng
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Sprache:eng
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