Lipopolysaccharide accelerates peristalsis by stimulating glucagon‐like peptide‐1 release from L cells in the rat proximal colon

Upon epithelial barrier dysfunction, lipopolysaccharide (LPS) stimulates glucagon‐like peptide‐1 (GLP‐1) secretion from enteroendocrine L cells by activating Toll‐like receptor 4 (TLR4). Because GLP‐1 accelerates peristalsis in the proximal colon, the present study aimed to explore whether LPS facil...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of physiology 2024-10, Vol.602 (19), p.4803-4820
Hauptverfasser:	Nakamori, Hiroyuki, Niimi, Atsuko, Mitsui, Retsu, Hashitani, Hikaru
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspirin Bacterial infections Calcitonin Colon colonic motility Epithelial cells Excretion Gastric motility Glucagon glucagon‐like peptide‐1 Gram-negative bacteria Immunohistochemistry Infections L cells leaky gut lipopolysaccharide Lipopolysaccharides Peptides Peristalsis Reactive oxygen species Therapeutic targets TLR4 protein Toll-like receptors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!