Dual-responsive two-photon probe for specific lipid droplets near-infrared fluorescence imaging in the brain of epileptic mice

Abnormal lipid metabolism in glial cells is a key pathological feature of epilepsy. The identification of lipid droplets (LDs) is essential for investigating lipid metabolism, disease progression, and potential therapeutic interventions. Two-photon imaging technology enables real-time visualization...

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Veröffentlicht in:	Biosensors & bioelectronics 2025-01, Vol.267, p.116774, Article 116774
Hauptverfasser:	Liu, Ji, Luo, Man, Gao, Weijie, Duan, Kunyuan, Bian, Haojun, Jin, Zhiyuan, Pan, Yuhan, Wang, Shiya, Gu, Yueqing, Zheng, Jinrong, Li, Ruixi, Yuan, Zhenwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biosensing Techniques - methods Brain - diagnostic imaging Brain - metabolism Epilepsy Epilepsy - diagnostic imaging Epilepsy - metabolism Fluorescent Dyes - chemistry Humans Lipid droplets Lipid Droplets - chemistry Lipid Droplets - metabolism Lipid Metabolism Mice Microscopy, Fluorescence, Multiphoton - methods Optical Imaging - methods Photons Polarity Two-photon imaging Viscosity
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